开国银副教授,
男，理学博士，1977年3月27日生，汉族，中共党员，上海师范大学生命与环境科学学院硕士生导师,上海师范大学植物生物工程实验室负责人。江苏省药用植物生物技术重点实验室兼职教授,上海市遗传学会理事，上海市植物生理学会会员，中国遗传学会会员。2000年至2002年，在复旦大学遗传工程国家重点实验室客座研究。2005年毕业于上海交通大学获生物化学与分子生物学专业博士学位,并于2005年6月破格晋升为副教授。主要从事植物分子生物学及药用植物代谢工程研究，近期在国内外学术期刊如PLANT
SCIENCE, JOURNAL OF BIOCHEMSITRY AND MOLECULAR BIOLOGY,
JOURNAL OF BIOSCIENCE, BIOLOGIA PLATARUM, PLANTA, DNA
SEQUENCE, BIOLOGIA, JOURNAL OF PLANT BIOCHEMISTRY AND
BIOTECHNOLOGY及PNAS等上发表生物技术领域文章40多篇，其中SCI收录22篇，申请中国发明专利8项（授权4项），在国际GenBank登录全长新基因20多条。2005年荣获“上海市优秀毕业生”称号。2006年入选“上海市青年科技启明星”人才计划。2007年被评为“上海师大优秀青年教师”。
学历、工作经历简介
1995. 09－1999.
06
徐州师范大学生命科学学院（学士）
1999. 09－2002.
06
福建农业大学生物技术中心（硕士）
2000. 12－2002.
06 复旦大学遗传工程国家重点实验室（客座研究）
2002. 09－2005.
06 上海交通大学生命科学技术学院（博士）
2005. 06—现在 上海师范大学生物系任教（副教授）
主要研究领域
1．植物分子生物学
2．药用植物代谢工程
3．基因克隆及表达调控
研究工作简介
主要从事植物分子生物学及药用植物代谢工程方面的教学和科研工作。主持和参加了国家及省部级科研项目10多项。近期在国内外学术期刊如PLANT
SCIENCE, JOURNAL OF BIOCHEMSITRY AND MOLECULAR BIOLOGY,
JOURNAL OF BIOSCIENCE, BIOLOGIA PLATARUM, PLANTA, DNA
SEQUENCE, BIOLOGIA, JOURNAL OF PLANT BIOCHEMISTRY AND
BIOTECHNOLOGY及PNAS等上发表生物技术领域文章40多篇，其中SCI收录22篇，在国际GenBank登录全长新基因20多条，申请中国发明专利8项（授权4项）。
近年来承担的科研项目
科研项目情况:
1.利用基因工程技术提高三分三中东莨菪碱含量的研究。2005.9-2007.12，上海市自然科学基金项目（主持）
2.喜树碱生物合成的代谢工程研究。2006.6
-2008.12，上海市青年科技启明星计划（主持）
3.云南省石斛种质资源的收集保护与开发利用。2006.8
-2008.12，上海市科委西部开发科技合作项目（主持）
4.利用毛状根转化技术获得三分三莨菪生物碱的研究。2006.6
-2008,上海市教委面上项目（主持）
5.多功能樱桃番茄新品种的培育。2007.9
-2009.12，上海市科委振兴东北科技合作项目（合作单位主持）
科研获奖
2006年入选“上海市青年科技启明星”人才计划
2007年被评为“上海师大优秀青年教师”。
申请专利：
1.开国银、苗志奇、唐克轩.红豆杉3-羟基-3-甲基戊二酰辅酶A合成酶蛋白编码序列（已授权）专利号ZL200410024891.0
2.开国银，陈军峰，李礼，周伟，周根余.三分三莨菪碱6β-羟化酶蛋白及其编码基因与用途.中国发明专利申请号200610118927.0
3.开国银，陆杨，钱忠英，周伟，周根余.龟背竹凝集素蛋白及其编码基因与应用.中国发明专利申请号:200610118926.6
4.唐克轩、开国银、苗志奇、李柱刚、赵凌侠。红豆杉凝集素蛋白编码序列（已授权）专利号ZL200410016709.7
5.唐克轩、开国银、苗志奇、李柱刚、赵凌侠。红豆杉紫杉烷C13－侧链－N－苯甲酰转运酶蛋白编码序列（已授权）专利号ZL200410016769.9
6.唐克轩,李柱刚，赵凌侠，孙小芬，开国银。大白菜BcpFLC3蛋白编码序列（已授权）。专利号为ZL03116982.1
7.唐克轩、开国银、孙小芬、庞永珍、姚剑虹、郑金贵。一种韭莲凝集素蛋白及其编码序列。中国专利发明申请号：02111817.5；公开号CN1459503A
8.蒋继宏、曹小迎、开国银、陈风美。杜仲3-羟基-3-甲基戊二酰辅酶A还原酶蛋白编码序列。中国专利发明申请号:200410065000.6，公开号CN1760363
近期发表的论文
(2002年以来)
1.Guoyin Kai*,
Junfeng Chen, Li Li, Genyu Zhou, Limin Zhou, Lei Zhang,
Yuhui Chen, Linxia Zhao. Molecular cloning and
characterization of a new cDNA encoding hyoscyamine
6β-hydroxylase from roots of Anisodus acutangulus.Journal
of Biochemistry and Molecular Biology,2007,40(5):
715- 722 (SCI Journal)
2.Guoyin
Kai*, Yang Lu, Zhongying Qian,
Yongting Luo, Genyu Zhou, Kexuan Tang. Molecular
characterization and expression analysis of a gene
encoding mannose -binding lectin from bulb of
Zephyranthes grandiflora. Biologia－section
Cellular and Molecular Biology
2006，61(6)：671-677(SCI
Journal)
3.Guoyin
Kai, Zhiqi Miao, Lei Zhang, Dongli Zhao, Zhihua Liao, Xiaofen Sun, Lingxia
Zhao, Kexuan Tang. Molecular cloning and expression
analyses of a new gene encoding
3-hydroxy-3-methylglutaryl -CoA synthase from Taxus x
media. Biologia Plantarum 2006,50(3):
359-366(SCI Journal)
4.Binhui
Guo+,Guoyin Kai+,Yifu
Gong,Hongbin Jin, Yechun Wang, Zhiqi Miao, Xiaofen Sun,
Kexuan Tang. Molecular cloning and heterologous
expression of a 10-deacetylbaccatin III-10-O-acetyl
transferase cDNA from Taxus x media. Molecular
biology reports 2007,34:89-95 (co-first author,
SCI Journal)
5.Guoyin
Kai, Jihong Jiang, Dongli Zhao, Lingxia Zhao,
Lei Zhang, Zhugang Li, Binhui Guo, Xiaofen Sun, Zhiqi
Miao, Kexuan Tang. Isolation and expression profile
analysis of a new cDNA encoding
5-alpha-taxadienol-10-beta-hydroxylase from Taxus
media. Journal of Plant Biochemistry and
Biotechnology 2006,15(1): 1-5(SCI
Journal)
6.Guoyin
Kai, Lingxia Zhao, Lei Zhang, Zhugang Li, Binhui
Guo, Dongli Zhao, Xiaofen Sun, Zhiqi Miao, Kexuan Tang.
Characterization and expression profile analysis of a
new cDNA encoding taxadiene synthase from Taxus media.
Journal of Biochemistry and Molecular Biology
2005,38(6): 675-685(SCI
Journal)
7.Guoyin
Kai, Zhiqi Miao, Chengxiang Qiu, Lei Zhang,
Lingxia Zhao, Zhugang Li, Tiefeng Xu, Lida Zhang, Yifu
Gong, Dongli Zhao, Donghui Liu, Xiaofen Sun, Kexuan
Tang. Molecular cloning and characterization of a
taxadienol acetyl transferase cDNA from Taxus media.
Plant science 2004,167(4):759-764(SCI
Journal)
8.Guoyin
Kai, Lingxia Zhao, Jingui Zheng, Lei Zhang,
Zhiqi Miao, Xiaofen Sun, Kexuan Tang. Isolation and
characterization of a new mannose-binding lectin gene
from Taxus media. Journal of Biosciences
2004,29(4):399-407 (SCI Journal)
9.Guoyin
Kai, Jingui Zheng, Lei Zhang, Yongzheng
Pang, Zhihua Liao, Zhugang Li, Lingxia Zhao, Xiaofen
Sun, Kexuan Tang. Molecular Cloning of a New Lectin Gene
from Z. grandiflora. DNA Sequence
2003,14(4):335-338 (SCI Journal)
10.Lei
Zhang+, Guoyin Kai+,
Beibei Lu, Hanming Zhang, Kexuan Tang, Jihong Jiang,
Wansheng Chen. Metabolic Engineering of Tropane Alkaloid
Biosynthesis in Plants. Journal of Integrative
Plant Biology 2005, 47(2): 136-143 (SCI
Journal，co-first
author)
11.Guoyin
Kai, Lei Zhang, Hongyu Zhang, Tiefeng Xu, Kexuan
Tang, Hanming Zhang. Marker free: a novel tendency of
transgenic plants. Acta Botanica Sinica.2002,44(8):883–888
(SCI Journal)
12.Binghui Guo, Guoyin Kai, Hongbing Jin,
Kexuan Tang. Taxol synthesis. African Journal of
Biotechnology.2006,5(1):15-20(SCI
Journal)
13.Lei
Zhang, Guoyin Kai, Tiefeng Xu, Yan Pi,
Hanming Zhang, Xiaofen Sun, Kexuan Tang. Efficient
regeneration of tetraploid Isatis indigotica plants via
adventitious organogenesis from hypocotyl explants.
Biologia Plantarum, 2004, 48(1):121-124
(SCI Journal)
14.Zhihua Liao, Yifu Gong, Guoyin Kai,
Kaijin Zuo, Min Chen, Qiumin Tan, Yamin Wei,Liang
Guo,Feng Tan, Xiaofen Sun, Kexuan Tang. An Intron-free
Methyl Jasmonate Inducible Geranylgeranyl Diphosphate
Synthase Gene from Taxus media and its functional
identification in yeast. Molecular Biology.2005，39(1):14-20.(SCI
Journal)
15.Jihong Jiang, Guoyin Kai, Xiaoyin Cao,
Fengmei Chen, Dongning He, Qun Liu. Molecular cloning
and function identification of a new HMG-CoA reductase
gene from Eucommia ulmoides Olive.
Bioscience reports 2006,26(2):171-181(SCI
Journal)
16.Zhonghai Chen, Guoyin Kai, Xiaojun Liu,
Juan Lin, Xiaofen Sun, Kexuan Tang. Molecular cloning
and characterization of a mannose-binding lectin gene
from Zingiber officinale Roscoe (ginger) rhizomes
Journal
of Biosciences 2005, 30(2): 213-220 (SCI
Journal)
17.Zhugang Li, Lingxia Zhao, Guoyin Kai,
Shunwu Yu, Youfang Cao, Yongzhen Pang, Xiaofen Sun,
Kexuan Tang. Cloning and expression analysis of a water
stress-induced gene from Brassica oleracea. Plant
physiology and biochemistry. 2004, 42(10):
789-794.(SCI Journal)
18.Zhugang Li, Chongshi Cui,Lingxia Zhao, Guoyin
Kai, Lida Zhang, Xiaofen Sun, Kexuan Tang.
Molecular cloning and characterization of an
anti-bolting related gene (BcpFLC3) from Brassica
campestris ssp.Pekinensis. Plant Science
2005, 168: 407-413 (SCI Journal)
19.Lingxia Zhao, Chengxiang Qiu, Jingfu Li, Yourong
Chai, Guoyin Kai, Zhugang Li, Xiaofen Sun,
Kexuan Tang. Investigation of disease resistance and
cold tolerance of Solanum lycopersicoides for tomato
improvement. HortScience 2005, 40(1):43-46
(SCI Journal)
20.Yifu
Gong, Zhihua Liao, Min Chen, Kaijin Zuo, Liang Guo,
Qiumin Tan, Zhushi Huang, Guoyin Kai,
Xiaofen Sun, Feng Tan, Kexuan Tang. Molecular cloning
and characterization of a 1-deoxy-D-xylulose 5-phosphate
reductoisomerase gene from Ginkgo biloba.
DNA Sequence 2005，16(2):111-120
(SCI Journal)
21.Zhao,
D., Li, L., Wang, Q., Kai, G., Wang, X., Wang, L., Sun,
F. and Tang K.Cloning
of taxane 2α-O-benzoyltransferase (TBT) genomic DNA from
Taxus.
Biologia-Section Cellular
and Molecular Biology
2006,61(3): 327-329
(SCI
Journal)
22.Linxia Zhao, Jingfu Li, Yourong Chai, Guoyin
Kai, Youfang Cao, Xiaofen Sun, Kexuan Tang.
Investigation on genetic relationship and cross
compatibility of S.lycopersicoides and lycopersicno.
Pakistan Journal of Biological Sciences.
2006,9(6):1160-1168
23.Lei
Zhang, Ruxian Ding, Yourong Chai, Mercedes Bonfill, M.
Teresa Piñol, Tiefeng Xu, Yan Pi, Zinan Wang, Hanming
Zhang, Guoyin Kai, Zhihua Liao, Xiaofen
Sun, Kexuan Tang. Engineering tropane biosynthetic
pathway in Hyoscyamus niger hairy root cultures.
Proc Natl Acad Sci U S A，2004,
101(17):6786-6791. (SCI Journal)
24.Zhang
Lei, Huang BeiBei, Kai GuoYin, Guo MeiLi.
Analysis of inter-population genetic variation in
Chinese Carthamus tinctorius L. using AFLP markers.
Acta Pharmaceutica Sinica 2006,41(1):91-96
25.Zhao,
D., Wang, Q., Kai, G., Wang, X., Lin, J.,
Pi, Y., Miao, Z., Sun, X. and Tang K. Molecular cloning
and characterization of cDNA encoding taxane
2α-O-benzoyltransferase (TBT), catalyzing taxol
biosynthesis from Taxus media. Journal of
Biological Sciences 2006,6(4)：651－658.
26.Guoyin
Kai*, Junfeng Chen, Wei Zhou, Liming
Dai, Genyu Zhou. Cloning and Sequence Analysis of a
Cold-regulated Gene BnCOR14 from Brassica napus.
Acta Bot.Boreal.-Occident.Sin.
2007,27(1): 9-15
27.Zhang
L, Wang Z, Xia Y, Kai G, Chen W, Tang K.
Metabolic engineering of plant L-ascorbic acid
biosynthesis: recent trends and applications.
Critical Reviews in Biotechnology.2007, 27(3): (SCI
Journal, in press)
28.Lei
Zhang，Bin
Yang，Beibei
Lu，Guoyin
Kai，
Zinan Wang，Yang
Xia，
Ruxian Ding，
Hanming Zhang，
Xiaofen Sun，Wansheng
Chen，Kexuan
Tang. Effect of methyl jasmonate on tropane alkaloid
production in transgenic Hyoscyamus niger hairy root
cultures overexpressing pmt gene. Planta,
2007,225(4):887-896(SCI Journal)
出版的著作目录
暂无
其他奖励
1．2003获“国家优秀奖学金”
2．2004获“上海交大优秀共产党员”
3．2005年获“上海市优秀毕业生”称号。
