黄学辉 教授
发布人:吴波  发布时间:2017-04-18   浏览次数:760

1. 个人简介:

黄学辉博士,教授,遗传学专业,博士生导师。建成了一整套全新的计算生物学方法,成功地应用于作物群体遗传学分析和复杂农艺性状的遗传解析,在水稻、谷子、芝麻等作物的全基因组遗传变异鉴定、复杂农艺性状的遗传基础解析、杂种优势机理的分析和探索栽培稻的驯化起源方面都取得了重要进展,主要研究成果以责任作者或第一作者发表在Nature(两篇),Nature Genetics(三篇), Nature Communications(两篇), Genome Research等国际一流期刊上论文。应邀在Annual Review of Plant Biology, Nature Genetics, Current Opinion in Plant Biology等重要学术杂志上撰写综述。2016年起兼任BMC plant biology的副主编。(邮箱:xhhuang@shnu.edu.cn)


2. 主要研究方向:

[1] 作物杂种优势的分子机理。

[2] 作物复杂品质性状的遗传解析。

[3] 基因组学大数据的计算生物学方法。


3. 近5年主持的省部级以上科研项目:

1、国家自然科学基金优秀青年基金项目(31322028) 2014-2016

2、国家自然科学基金重大研究计划重点项目(91535202)2016-2017

3、国家自然科学基金重大研究计划集成项目(91635302)2017-2018

4、十二五863水稻功能基因组,子课题负责人(2012AA10A304) 2012-2015

5、国家重点研发计划水稻品质与养分利用功能基因组课题负责人(2016YFD0100902) 2016-2020

6、上海市启明星人才项目(13QA1403900) 2013-2015

7、中国科学院卓越青年科学家项目2014-2015


4. 近5年发表论文及出版著作:

论文

1.Huang X, Yang S, Gong J, Zhao Q, Feng Q, Zhan Q, Zhao Y, Li W, Cheng B, Xia J, Chen N, Huang T, Zhang L, Fan D, Chen J, Zhou C, Lu Y, Weng Q, Han B. Genomic architecture of heterosis for yield traits in rice. Nature 537:629-633 (2016).(共同通讯作者)

2.Huang X, Kurata N, Wei X, Wang Z-X, Wang A, Zhao Q, Zhao Y, Liu K, Lu H, Li W, Guo Y, Lu Y, Zhou C, Fan D, Weng Q, Zhu C, Huang T, Zhang L, Wang Y, Feng L, Furuumi H, Kubo T, Miyabayashi T, Yuan X, Xu Q, Dong G, Zhan Q, Li C, Fujiyama A, Toyoda A, Lu T, Feng Q, Qian Q, Li J, Han B. A map of rice genome variation reveals the origin of cultivated rice.Nature 490: 497-501 (2012).

3.Huang X, Zhao Y, Wei X, Li C, Wang A, Zhao Q, Li W, Guo Y, Deng L, Zhu C, Fan D, Lu Y, Weng Q, Liu K, Zhou T, Jing Y, Si L, Dong G, Huang T, Lu T, Feng Q, Qian Q, Li J, Han B. Genome-wide association study of flowering time and grain yield traits in a worldwide collection of rice germplasm. Nat. Genet. 44: 32-39 (2012).

4.Huang X, Wei X, Sang T, Zhao Q, Feng Q, Zhao Y, Li C, Zhu C, Lu T, Zhang Z, Li M, Fan D, Guo Y, Wang A, Wang L, Deng L, Li W, Lu Y, Weng Q, Liu K, Huang T, Zhou T, Jing Y, Li W, Lin Z, Buckler ES, Qian Q, Zhang Q, Li J, Han B. Genome-wide association studies of 14 agronomic traits in rice landraces. Nat. Genet. 42: 961-967 (2010).

5.Jia G, Huang X, Zhi H, Zhao Y, Zhao Q, Li W, Chai Y, Yang L, Liu K, Lu H, Zhu C, Lu Y, Zhou C, Fan D, Weng Q, Guo Y, Huang T, Zhang L, Feng Q, Hao H, Liu H, Lu P, Zhang N, Li Y, Guo E, Wang S, Wang S, Liu J, Zhang W, Chen G, Zhang B, Li W, Wang Y, Li H, Zhao B, Li J, Diao X, Han B. A haplotype map of genomic variations and genome-wide association studies of agronomic traits in foxtail millet (Setaria italica). Nat. Genet.45: 957-961 (2013).

6.Huang X and Han B. A crop of maize variants. Nat. Genet.44: 734-735 (2012).(共同通讯作者)

7.Wei X, Liu K, Zhang Y, Feng Q, Wang L, Zhao Y, Li D, Zhao Q, Zhu X, Zhu X, Li W, Fan D, Gao Y, Lu Y, Zhang X, Tang X, Zhou C, Zhu C, Liu L, Zhong R, Tian Q, Wen Z, Weng Q, Han B, Huang X, Zhang X.Genetic discovery for oil production and quality in sesame.Nat Commun. 6:8609 (2015).(共同通讯作者)

8.Huang X, Yang S, Gong J, Zhao Y, Feng Q, Gong H, Li W, Zhan Q, Cheng B, Xia J, Chen N, Hao Z, Liu K, Zhu C, Huang T, Zhao Q, Zhang L, Fan D, Zhou C, Lu Y, Weng Q, Wang Z-X, Li J, Han B. Genomic analysis of hybrid rice varieties reveals numerous superior alleles that contribute to heterosis.Nat. Commun. 6:6258 (2015).

9.Huang X and Han B. Natural variations and genome-wide association studies in crop plants. Annu. Rev. Plant Biol. 65: 531-551 (2014).(共同通讯作者)

10.Han B, Huang X. Sequencing-based genome-wide association study in rice. Curr Opin Plant Biol. 16: 133-138 (2013).(共同通讯作者)

11.Huang X, Zhang Q, Han B. Comparative population genomics reveals strong divergence and infrequent introgression between Asian and African rice. Mol. Plant. 8:958-960 (2015).(通讯作者)

12.Huang X. From genetic mapping to molecular breeding: genomics have paved the highway. Mol. Plant.9:959-960 (2016).(通讯作者)

13.Chen E, Huang X, Han B. How can rice genetics benefit from rice-domestication study? Natl Sci Rev 3: 278-280 (2016).(共同通讯作者)

14.Huang X, Lu T, Han B. Resequencing rice genomes: an emerging new era of rice genomics. Trends Genet. 29: 225-232 (2013).

15.Ohyanagi H, Ebata T, Huang X, Gong H, Fujita M, Mochizuki T, Toyoda A, Fujiyama A, Kaminuma E, Nakamura Y, Feng Q, Wang ZX, Han B, Kurata N. OryzaGenome: Genome Diversity Database of Wild Oryza Species. Plant Cell Physiol. 57:e1 (2016).

16.Li XM, Chao DY, Wu Y, Huang X, Chen K, Cui LG, Su L, Ye WW, Chen H, Chen HC, Dong NQ, Guo T, Shi M, Feng Q, Zhang P, Han B, Shan JX, Gao JP, Lin HX. Natural alleles of a proteasome α2 subunit gene contribute to thermotolerance and adaptation of African rice. Nat Genet. 47:827-833 (2015).

17.Chen C, Chen H, Lin YS, Shen JB, Shan JX, Qi P, Shi M, Zhu MZ, Huang X, Feng Q, Han B, Jiang L, Gao JP, Lin HX. A two-locus interaction causes interspecific hybrid weakness in rice. Nat. Commun. 5: 3357 (2014).

18.Si L, Chen J, Huang X, Gong H, Luo J, Hou Q, Zhou T, Lu T, Zhu J, Shangguan Y, Chen E, Gong C, Zhao Q, Jing Y, Zhao Y, Li Y, Cui L, Fan D, Lu Y, Weng Q, Wang Y, Zhan Q, Liu K, Wei X, An K, An G, Han B. OsSPL13 controls grain size in cultivated rice. Nat. Genet. 48: 447-456 (2016).

19.Liu H, Shi J, Sun C, Gong H, Fan X, Qiu F, Huang X, Feng Q, Zheng X, Yuan N, Li C, Zhang Z, Deng Y, Wang J, Pan G, Han B, Lai J, Wu Y. Gene duplication confers enhanced expression of 27-kDa γ-zein for endosperm modification in quality protein maize. Proc. Natl. Acad. Sci. USA. 113: 4964-1969 (2016).

20.Peng Z, Lu Y, Li Y, Zhao Q, Feng Q, Gao Z, Lu HY, Hu T, Yao N, Liu K, Li Y,Fan D, Guo G, Li W, Lu Y, Weng Q, Zhou C, Zhang L, Huang T, Zhao Y, Zhu C, Liu X, Yang X, Wang T, Miao K, Zhuang Z, Cao X, Tang W, Li G, Liu Y, Chen J, Liu Z, Yuan L, Liu Z, Huang X, Lu T, Fei B, Ning Z, Han B, Jiang Z. The draft genome of the fast-growing non-timber forest species moso bamboo (Phyllostachys heterocycla). Nat. Genet.45: 456-461 (2013).

21.Luo J, Liu H, Zhou T, Gu B, Huang X, Shangguan Y, Zhu J, Li Y, Zhao Y, Wang Y, Zhao Q, Wang A, Wang Z, Sang T, Wang Z, Han B.An-1 encodes a basic helix-loop-helix protein that regulates awn development, grain size, and grain number in rice.Plant Cell 25:3360-3376 (2013).

22.Li S, Yan S, Wang A, Zou G, Huang X, Han B, Qian Q, Tao Y. Identification of QTLs associated with tissue culture response through sequencing-based genotyping of RILs derived from 93-11 3 Nipponbare in rice (Oryza sativa). Plant Cell Rep. 32: 103-116 (2012).

23.Wang L, Wang A, Huang X, Zhao Q, Dong G, Qian Q, Sang T, Han B. Mapping 49 quantitative trait loci at high resolution through sequencing-based genotyping of rice recombination inbred lines. Theor. Appl. Genet.122:327-340 (2011).


著作:

24.Huang X and Han B. Chapter 3: Natural variation and sequencing-based genetics studies. “Genetics and Genomics of Rice” Springer Press (2013).


5. 近5年获奖情况:

中国科学院杰出科技成就奖2013年度

赛诺菲优秀人才奖2014年度

中国科学院卢嘉锡青年人才奖2013年度

明治生命科学奖优秀奖2012年度


6. 近5年申请、授权专利情况:

徐群,韩斌,魏兴华,黄学辉,龚浩,冯跃,袁筱萍,余汉勇,王一平。一种用于水稻品种鉴定的SNP芯片、制备方法及用途。公开号:CN104328507A.