赵宝国
发布人:系统管理员  发布时间:2017-04-22   浏览次数:263



1. 个人简介:

赵宝国 (Baoguo Zhao)博士,教授,有机化学专业硕士/博士生导师1996于武汉大学化学系获理学学士学位,2002年于南京大学化学系获理学硕士学位,2006中国科学院上海有机化学研究所理学博士学位,2006-2011年于美国科罗拉多州立大学化学系做博士后研究,2011年加入上海师范大学。Email: zhaobg2006@shnu.edu.cn

  

2. 主要研究方向:

[1] 新型有机反应的发展

[2] 不对称催化

[3] 天然产物全合成

  

3. 发表论文:

[39] Feng Liu, Jiaxin Tian, Yong Liu, Chuangan Tao, Hao Zhu, Aina Zhang, Dongfang Xu and Baoguo Zhao* “Decarboxylative Umpolung of Conjugated Enal to β-Carbanion for Intramolecular Nucleophilic Addition to Aldehyde” Org. Chem. Fron. in review.

[38]Xiaoyu Lan, Chuangan Tao, Xuliang Liu, Aina Zhang, Baoguo Zhao* “Asymmetric Transamination of α-Keto Acids Catalyzed by Chiral Pyridoxamines” Org. Lett. 201618, 3658.

[37]Yong Ethan Liu, Zhaole Lu, Bo Li, Jiaxin Tian, Feng Liu, Junyu Zhao, Chengkang Hou, Yingkun Li, Lili Niu, Baoguo Zhao* “Enzyme-Inspired Axially Chiral Pyridoxamines Armed with a Cooperative Lateral Amine Chain for Enantioselective Biomimetic Transamination” J. Am. Chem. Soc.2016138, 10730.

[36]Jianfeng Chen, Junyu Zhao, Xing Gong, Dongfang Xu *, Baoguo Zhao * “A new type of chiral-pyridoxamines for catalytic asymmetric transamination of a-keto acids” Tetrahedron Lett.201657, 4612.

[35]Limin Shi, Chuangan Tao, Qin Yang, Yong Ethan Liu, Jing Chen, Jianfeng Chen, Jiaxin Tian, Feng Liu, Bo Li, Yongling Du, Baoguo Zhao* “Chiral Pyridoxal-Catalyzed Asymmetric Biomimetic Transamination of α-Keto Acids” Org. Lett.201517, 5784.

[34]Bin Rong, Qin Yang, Hong Xu, Yifan Hu, Xuejing Cheng, Yong Liu, Baoguo Zhao* “Pd-catalyzed Asymmetric α-Allylic Alkylation of Thioamides” Tetrahedron Lett.201556, 595.

[33]Juan Xu, Jing Chen, Lei Ding, Xuliang Liu, Dongfang Xu, Baoguo Zhao* “Synthesis of α-Methylene-γ-amino acid Esters from Aldehydes via Aminative Umpolung Strategy” Adv. Synth. Catal. 2014356, 3219.

  

[32]Xuliang Liu, Ang Gao, Lei Ding, Juan Xu, Dongfang Xu, Baoguo Zhao* “Aminative Umpolung Synthesis of Vicinal Amines from Aromatic Aldehydes”Org. Lett. 201416, 2118.

  

[31]Lei Ding, Jing Chen, Yifan Hu, Juan Xu, Xing Gong, Dongfang Xu, Baoguo Zhao*, Hexing Li “Aminative Umpolung of Aldehydes to α-Amimo Anion Equivalents for Pd-catalyzed Allyation: An Efficient Synthesis of Homoallylic Amines” Org. Lett.201416, 720.

  

[30]Bing Rong, Lei Ding, Hailei Yu, Qing Yang, Xuliang Liu, Dongfang Xu, Baoguo Zhao* Pd-Catalyzed Allylic Alkylation of Thioamides”Tetrahedron Lett. 2013, 54, 6501.

  

[29]Baoguo Zhao, Zhaobin Han, Kuiling Ding* “N-H Functions in Organometallic Catalysis” Angew. Chem. Int. Ed.2013, 52, 4744.

  

[28]Hailei Yu, Xuliang Liu, Lei Ding, Qin Yang, Bin Rong, Ang Gao, Baoguo Zhao*, Haifeng Yang “Pd-Catalyzed α-Arylation of Thioamides” Tetrahedron Lett.201354, 3060.

  

[27]Richard G. Cornwall, Baoguo Zhao, Yian Shi* “Catalytic Asymmetric Synthesis of Cyclic Sulfamides from Conjugated Dienes Org. Lett.201315, 796.

  

[26]Yingguang Zhu, Baoguo Zhao, Yian Shi* “Highly Efficient Cu(I)-Catalyzed Oxidation of Alcohols to Ketones and Aldehydes with DiaziridinoneOrg. Lett.201315, 992.

  

[25]Thomas A. Ramirez, Baoguo Zhao and Yian Shi* “Recent advances in transition metal-catalyzed sp3 C–H amination adjacent to double bonds and carbonyl groups” Chem. Soc. Rev.201241, 931-942.

[24]Baoguo Zhao, Xingao Peng, Yingguang Zhu, Thamos A. Ramirez, Richard G. Cornwall, Yian Shi* “Cu(I)-Catalyzed Diamination of Conjugated Dienes. Complementary Regioselectivity from Two Distinct Mechanistic Pathways” J. Am. Chem. Soc.2011133, 20890-20900.

  

[23]Xingao Peng, Yingguang Zhu, Thomas A. Ramirez, Baoguo Zhao, Yian Shi* “New Reactivity of Oxaziridine: Pd(II)-Catalyzed Aromatic C-H Ethoxycarbonylation via C-C Bond Cleavage” Org. Lett.201113, 5244-5247.

  

[22]Richard G. Cornwall, Baoguo Zhao, Yian Shi* “Complementary Regioselectivity in the Cu(I)-Catalyzed Diamination of Conjugated Dienes To Form Cyclic SulfamidesOrg. Lett.201113, 434-437.

  

[21]Baoguo Zhao, Xingao Peng, Sunliang Cui, Yian Shi* “Cu(I)-catalyzed Regioselective Diamination of Conjugated Dienes via Dual Mechanistic Pathways” J. Am. Chem. Soc.2010132, 11009-11011.

  

[20]Baoguo Zhao, Haifeng Du, Sunliang Cui, Yian Shi* “Synthetic and Mechanistic Studies of Pd(0)-Catalyzed Diamination of Conjugated Dienes” J. Am. Chem. Soc.2010132, 3523-3532.

  

[19]Baoguo Zhao, Haifeng Du, Renzhong Fu, Yian Shi* Pd(0)-Catalyzed Asymmetric Allylic and Homoallylic Diamination of 4-Phenyl-1-butene with Di-tert-butyldiaziridinone” Org. Synth. 2010, 87, 263.

  

[18]Thamos A. Ramirez, Baoguo Zhao, Yian Shi*“An effective C-C Double bond formation via Cu(I)-Catalyzed dehydrogenation” Tetrahedron Lett.201051, 1822-1825.

  

[17]Baoguo Zhao, Haifeng Du, Yian Shi*“Cu(I)-catalyzed Diamination of Conjugated Olefins with Tunable Counteranions. A Possible Approach to Asymmetric Diamination”J. Org. Chem.2009,74, 8392-8395.

  

[16]Baoguo Zhao, Haifeng Du, Yian Shi*“Cu(I)-Catalyzed C-H α-Amination of Aryl Ketones: Direct Synthesis of Imidazolinones”J. Org. Chem.2009,74, 4411-4413.

  

[15]Yuehong Wen, Baoguo Zhao, Yian Shi* “Cu(I)-Catalyzed Diamination of Disubstituted Terminal Olefins: An Approach to Potent NK1 Antagonist” Org. Lett.200911, 2365-2368.

  

[14]Rengzhong Fu, Baoguo Zhao, Yian Shi* “Synthesis of (+)-CP-99,994 via Pd(0)-Catalyzed Asymmetric Allylic and Homoallylic C-H Diamination of Terminal Olefin”J. Org. Chem.2009,74, 7577-7580.

  

[13]Haifeng Du, Baoguo Zhao, Yian Shi* Pd(0)-Catalyzed Diamination of trans-1-Phenyl-1,3-butadiene with Di-tert-butyldiaziridinone as Nitrogen Source” Org. Synth.200986, 315.

  

[12]Baoguo Zhao, Haifeng Du, Yian Shi*“A Cu(I)-Catalyzed C-α-Amination of Esters. Direct Synthesis of Hydantoins”J. Am. Chem. Soc.2008130, 7220-7221.

  

[11]Baoguo Zhao, Haifeng Du, Yian Shi*“Cu(I)-Catalyzed Cycloguanidination of Olefins” Org. Lett,200810, 1087-1090.

  

[10]Haifeng Du, Baoguo Zhao, Yian Shi* “Catalytic Asymmetric Allylic and Homoallylic Diamination of Terminal Olefins via Formal C-H Activation”J. Am. Chem. Soc.2008130, 8590-8591.

  

[9]Haifeng Du, Baoguo Zhao, Weicheng Yuan, Yian Shi* “Cu(I)-Catalyzed Asymmetric Diamination of Conjugated Dienes”Org. Lett.200810, 4231-4234.

  

[8]Baoguo Zhao, Xingao Peng, Zheng wang, Chungu Xia, Kuiling Ding* Modular Chiral Bidentate Phosphonites: Design, Synthesis, and Application in Catalytic Asymmetric Hydroformylation Reactions”Chem. Eur. J.200814, 7847-7857.

  

[7]Baoguo Zhao, Weicheng Yuan, Haifeng Du, Yian Shi* “Cu(I)-Catalyzed Intermolecular Diamination of Activated Terminal Olefins” Org. Lett.20079, 4943-4945.

  

[6]Haifeng Du, Baoguo Zhao, Yian Shi* “A Facile Pd(0)-Catalyzed Regio- and Stereoselective Diamination of Conjugated Dienes and Trienes” J. Am. Chem. Soc.2007129, 762-763.

  

[5]Haifeng Du, Weicheng Yuan, Baoguo Zhao, Yian Shi* “A Pd(0)-Catalyzed Diamination of Terminal Olefins at Allylic and Homoallylic Carbons via Formal C-H Activation under Solvent-Free Conditions” J. Am. Soc. Chem.2007129, 7496-7497.

  

[4]Haifeng Du, Weicheng Yuan, Baoguo Zhao, Yian Shi*“Catalytic Asymmetric Diamination of Conjugated Dienes and Triene” J. Am. Soc. Chem.2007129, 11688-11689.

  

[3]Weicheng Yuan, Haifeng Du, Baoguo Zhao, Yian Shi* “A Mild Cu(I)-Catalyzed Regioselective Diamination of Conjugated Dienes” Org. Lett.20079, 2589-2591.

  

[2]Baoguo Zhao, Zheng Wang, Kuiling Ding* “Practical by Ligand Design: A New Generation of Monodentate Phosphoramidite Ligands for Rhodium Catalyzed Enantioselective Hydrogenations” Adv. Synth. Catal.2006348, 1049-1057

  

[1]Min Zhang, Huiying An, Baoguo Zhao, Jianhua Xu* Aromatic annulation strategy for naphthalenes fused at 1,2- and 3,4-positions with two heterocycles” Org. Biomol. Chem.20064, 33-35.

  

4. 申请专利:

[6]赵宝国,刘勇,卢兆乐,李波,一种手性联芳骨架吡哆胺类催化剂及其合成方法与应用申请号:201610444057.X

[5]赵宝国,陈剑锋,赵濬宇,龚幸,一种新型手性开链吡哆胺催化剂及其合成方法与应用专利号:201610444112.5

[4]赵宝国,兰晓宇陶创安刘旭亮,一种手性吡哆胺催化剂及其合成方法和应用专利号:201610443128.4

[3]赵宝国,陈静,石力敏,刘勇,杨琴,陈剑锋,田家昕,陶创安,李波,许东芳“一种新型吡哆素衍生物及其制备方法”,专利号:201510413900.3

[2]赵宝国,陈静,杨琴,陈剑锋,石力敏,刘勇(Yong Ethan Liu),龚幸,兰晓宇,卢兆乐,刘勇 (Yong Liu),陶创安,田家昕,许东芳,“一种吡哆醛催化剂及其合成方法与应用”,专利号:201510415046.4

[1]赵宝国,陶创安,石力敏,刘勇,陈静,“一种手性吡哆醛催化剂及其合成方法与应用”,专利号:201510427177.4

  

5. 获奖情况:

[1] 入选上海市东方学者特聘教授2010年。

[2] 入选教育部新世纪优秀人才计划2012年。

[3] 入选上海市浦江人才计划2012年。

  


updated 2017 01